Abstract: The widespread intermediate-felsic intrusions in the Biezhentao-Boluokenu area along the northern margin of the Western Tianshan, Xinjiang, are genetically associated with a series of porphyry–skarn Cu-polymetallic deposits. The Aide copper deposit, recently discovered in the central Sailimu Micro-Block, is hosted in the contact zone between limestones and granodiorite intrusions. This study reports zircon U–Pb dating, whole-rock geochemical and zircon Hf isotopic analyses of the ore-related granodiorite, together with in situ S–Pb isotopic analyses of sulfides from the ores. The granodiorite was emplaced during the Early Carboniferous (357.9 ± 4.6 Ma) and belongs to the peraluminous high-K calc-alkaline series. It is enriched in large-ion lithophile elements (Rb, Th, U, K, Pb) and depleted in Ba and high-field-strength elements (Nb, P, Ti). Zircon ε_Hf(t) values range from −1.6 to +2.6 (average −0.2), suggesting that the magma was derived from partial melting of Mesoproterozoic crustal materials with the involvement of mantle-derived magmas. The granodiorite were formed in a continental arc setting related to the southward subduction of the North Tianshan Ocean beneath the Yili Block during the Late Paleozoic. The sulfides in the ores yield total δ³⁴S values of 7.28 ‰–8.92 ‰, with ²⁰⁶Pb/²⁰⁴Pb=18.320–18.400, ²⁰⁷Pb/²⁰⁴Pb=15.612–15.625, and ²⁰⁸Pb/²⁰⁴Pb=38.518–38.571, indicating that the ore-forming materials have a mixed crust-mantle source with the addition of strata-derived components. The Aide copper deposit shares a consistent timing of magmatism and mineralization and similar ore-material sources with other porphyry–skarn copper deposits along the northern margin of the Yili Block, Western Tianshan, showing a close spatiotemporal and genetic coupling. It is interpreted as part of a Late Devonian–Early Carboniferous porphyry–skarn Cu metallogenic system associated with intermediate-felsic intrusions in a continental arc setting.