Abstract: Sulphate acid water is often produced in the mining process of pyrite mines, which not only corrodes pipelines and equipment, endangers workers′ health, but also seriously pollutes water system, affects industry, agriculture and fishery production. Therefore, it is one of the urgent tasks to solve the environmental problems of pyrite mines. Systematic analysis of mine environmental problems, in-depth understanding of the formation mechanism of acid water, and proposed one or more methods of ecological restoration and treatment programs according to local conditions are effective ways for ecological restoration of acid water in pyrite mines. Taking Wuliba Pyrite Mine in Xixiang County of South Shaanxi Province as an example, based on the analysis of the environmental status and ecological environment problems of mine cave, waste residue, surface water and ground subsidence, the paper analyzes the root of acid water, puts forward the comprehensive treatment technology of "surface water treatment + groundwater treatment + geological disaster treatment + ecological restoration + end treatment + environmental monitoring", and finally explores three treatment modes of mine cave modification filling, waste residue resource utilization and grouting reinforcement in subsidence area.It provides a scientific reference for the ecological restoration of mines in similar areas.